The "Mediofondo" course of the World Championships in Trento is 86.8 km long. In the first 30 km, the course follows the Granfondo race, with the ascent of Bondone from Aldeno to the Le Viote plateau and the following descent towards Lasino and Calavino.

At that point, the Mediofondo riders will tackle a slight slope section that runs alongside Vezzano, Terlago and its lake. With around 20km to go, the peloton will once again tackle the climb of Bondone from Sopramonte to the village of Candriai.

At the top there will be 13 km to go, 10km downhill and 3km flat towards the finish in Trento, Le Albere quartier.